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The mission of the Northeast ALS Consortium (NEALS) is to rapidly translate
scientific advances into clinical research and new treatments for people
with Amyotrophic Lateral Sclerosis (ALS) and motor neuron disease.

Resources for Patients & Families
New Research Participation Survey for PALS
(September 9. 2014)
Researchers from the University of Michigan and University of Rochester are conducting a survey asking PALS for their perspectives and opinions on research participation.  The aim of the survey is to study how people understand different issues related to research participation such as their understanding of purpose and potential benefits and risks of research.  The long term goal of this project is to improve the informed consent process.

The survey is an online survey and takes about 5-8 minutes to complete.  It involves reading a short description of a hypothetical research study and then answering some questions asking for your opinion.   The survey is funded by a grant from the National Institutes of Health. 

If you are interested in the survey, please contact the researchers at this email address: They can provide further information and a link to the survey if you are interested in participating.

Statement on U.S. BrainStorm Trial
We have had many inquiries regarding the BrainStorm Stem Cell Therapeutics Clinical Trial. BrainStorm is currently conducting a Phase IIa dose-escalating trial at the Hadassah Medical Center in Israel. We are continuing to follow the progress of the study in Israel and will keep the NEALS website current on all new trials and start dates.

Protocol information and eligibility criteria for the BrainStorm trial can be found on the US Government’s clinical trials website. Please continue to check here for new developments about this trial.

Resources for Researchers
New Funding Announcement from the ATSDR
(January 15, 2015)
The federal Agency for Toxic Substances and Disease Registry (ATSDR) has just released a new funding announcement that allows for investigator-initiated R01 research that will further the understanding of potential risk factors for amyotrophic lateral sclerosis (ALS), while supporting the goals of the National ALS Registry. A full description of the announcement, along with submission deadlines can be found here

National ALS Registry for ALS Researchers
(June 1, 2014)
If you are an ALS Researcher and would like to use the National ALS Registry to help recruit ALS patients for your study, click here. To see a list of ALS Researchers who are already using the National ALS Registry's research notificaton tool to help recruit patients for their studies, click here.

NEALS Databases
NEALS has six de-identified ALS trial databases available for mining. Collected since the birth of NEALS, these ALS trial databases are a great resource for ALS research. Get the data >>
NEALS Samples
Samples from the NEALS repository are available to researchers for the purpose of furthering the understanding of ALS or motor neuron disease and developing disease biomarkers.
Get the samples>>

News & Events
Neuralstem Announces Topline Results of Phase II Trial
(March 12, 2015)
Neuralstem, Inc. announced top-line data from the Phase II trial of NSI-566 spinal cord-derived neural stem cells under development for the treatment of ALS. The maximum tolerated dose of 16 million transplanted cells and the surgery was well tolerated.

"We were very excited to participate as a site in this clinical trial," said Merit Cudkowicz, MD, Chief of Neurology, Massachusetts General Hospital and Co-Chair of NEALS." We are hopeful with respect to the top-line results and it is important to move swiftly and safely forward to a larger, confirmatory safety and efficacy study." The NEALS data and systems team participated in the study, under Hong Yu and Alex Sherman leadership. You can read the entire press release here.

2015 Annual NEALS Meeting

(February 2, 2015)
The 2015 Annual NEALS Meeting is currently scheduled for Wednesday, November 4 through Friday, November 6. More information for this conference will become available in Spring 2015!

NEALS Meeting at AAN
(February 1, 2015)
The NEALS meeting at AAN in Washington, DC has been officially scheduled for Wednesday morning, April 22nd 7:30 – 8:30am at the Marriott Marquis: Archives Room.

The 25th Annual MND/ALS Symposium 
(December 15, 2014)
The 25th Annual Symposium was held from December 5th – 7th in Brussels, Belgium. The International MND/ALS Symposium is the largest annual MND/ALS conference with over 900 researchers in attendance from around the globe. To read more about this years conference, click here.

ALS Researchers Appear on "The Doctors"
(November 25, 2014)
NEALS Co-Chair Merit Cudkowicz, MD, MSc (Massachusetts General Hospital) and NEALS member Robert Baloh, MD, PhD (Cedars-Sinai) appeared on an episode of "The Doctors" with PALS Nanci Ryder, a celebrity publicist who opened up about her ALS diagnosis. Check your local listings for show times, and view a short clip and article about the episode here.

PALS Speaks to Congress about ALS Research
(November 19, 2014)
Attorney and PALS Michael Gollin spoke to Congress November 18th about how they can help change the balance of risks to favor successful innovation in ALS research, and why they should adopt the MODERN Cures Act. You can read Michael’s full testimony at the MODDERN Cures Act Briefing here.

Dr. Cudkowicz Appears on "CBS This Morning"
(November 18, 2014)
NEALS Co-Chair Merit Cudkowicz, MD, MSc (Massachusetts General Hospital) appeared on “CBS This Morning” to discuss donations from the ALS ice bucket challenge, and the ways that the initiative has already aided researchers in identifying new targets for treatment. You can view the full piece here.

13th Annual NEALS Meeting
(November 11, 2014)
This year's annual NEALS meeting took place October 22nd-24th in Clearwater Beach, FL. Click here to read a full recap of the event.

Fourth Annual NEALS Clinical Research Learning Institute (CRLI)
(November 11, 2014)
This year's NEALS CRLI took place on October 24th and 25th in Clearwater Beach, FL and was our largest group yet! Read more about the event here.


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